Spontaneous pneumothorax and ozone levels: is there a relation?
نویسندگان
چکیده
STUDY OBJECTIVES Although links between meteorological conditions and spontaneous pneumothorax (SP) have been proposed, the reports are controversial. In this study ozone levels, which are known to have some adverse effects on lung tissues, were investigated as a potential triggering factor of SP. At present there is not sufficient information about the effects of ozone on SP. METHODS Of a total 79 pneumothorax patients recruited for the study, 21 secondary pneumothorax cases were excluded. In the remaining 58 SP patients, meteorological data at the time of SP occurrence were recorded. RESULTS The number of SP patients was higher in spring than in the other seasons (p < 0.05). There was an association between the SP frequency and the average ozone level at different seasons (F 3,52 = 19.45, p = 0.001). The average ozone level was higher in spring (363 ± 25 Dobson) than during the other seasons (autumn 296 ± 18 Dobson; summer 321 ± 26 Dobson; winter 324 ± 32 Dobson) (p = 0.001). There was a positive correlation between SP frequency and the average ozone values for each season (r = 0.301, p = 0.024). There was no significant correlation between the severity of SP and ozone level (r = 0.236, p = 0.16). CONCLUSIONS The number of SP patients increases in spring when ozone levels are highest. Ozone is known to affect alveolar cells and cause interstitial edema. Ozone causes damage to the lung interstitium by way of oxidative stress. Rupture of unrecognized underlying blebs/bullae has been proposed as a cause of SP. Increased levels of ozone may be a triggering factor for these ruptures.
منابع مشابه
تعیین درصد فراوانی انواع درمان پنوموتوراکس خودبهخودی در بیماران بستری در بیمارستان حضرت رسول اکرم(ص) در طی سالهای 1379 لغایت 1380
Background & Objective: Non-traumatic pneumothorax is mostly caused by the disruption of small and large bulla in lungs. Approximately 80% of the patients with spontaneous pneumothorax are thin, tall young men without the history of respiratory disorders. In patients over 40 years old there is a noticeable lung disease, mostly emphysema in smokers. Catamential pneumothorax is a rare phenom...
متن کاملRisk Factors of Pneumothorax at Aleppo University Hospitals
Spontaneous pneumothorax can be either primary due to the rupture of subpleural bleb or secondary due to underlying lung disease, usually bullous emphysema.1 Relatively little is known about the causative factors of spontaneous pneumothorax in Arab Countries.1 This is the first study and the primary step towards understanding the risk factors and causes of spontaneous pneumothorax in Syria.Syri...
متن کاملپنوموتوراکس خودبخودی: اپیدمیولوژی و درمان، بیمارستان های امام و بقیه الله (عج)، 81-1371
Spontaneous pneumothorax is a medical condition that potentially may be dangerous. Although several methods for management of this problem have been propounded, there is a great disagreement among the specialists about how to treat it and when more invasive treatments are indicated.Materials and Methods: This study carried out in two phases. In first phase, 26 patients who had admitted to Imam ...
متن کاملPnm-18: Maternal Exposure to Ozone, Nirogen Dioxide, Sulfur Dioxide and Spontaneous Abortion
Background: Adverse pregnancy outcomes (low birth weight, prematurity and intrauterine growth retardation) are associated with exposure to urban air pollution. Experimental data have also shown that such exposure elicits adverse reproductive outcomes. We examined association between spontaneous abortion of the first trimester of pregnancy and ambient concentrations of Ozone, Nirogen Dioxide and...
متن کاملپنوموتوراکس خودبخودی
A case with bilateral spontaneous pneumothorax was presented. Etiology, mechanism, and treatment were discussed on the review of literature. Spontaneous Pneumothorax is a clinical entity resulting from a sudden non traumatic rupture of the lung. Biach reported in 1880 that 78% of 916 patients with spontaneous pneumothorax had tuberculosis. Kjergaard emphasized 1932 the primary importance of sub...
متن کامل